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1-(2-Chloro-6-piperazin-1-yl-phenyl)-ethanone → HCID 21073566、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(2-Chloro-6-piperazin-1-yl-phenyl)-ethanone | HCID 21073144 | — |
| 反応物 | 4-(7-Oxo-7,8-dihydro-1,8-naphthyridin-2-yloxy)butanal | HCID 21073380 | — |
| 生成物 | HCID 21073566 | HCID 21073566 | — |
反応手順
In a manner similar to that of other examples above, 1-(2-chloro-6-piperazin-1-yl-phenyl)-ethanone was coupled by reductive amination to 4-(7-oxo-7,8-dihydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the title compound. MS: APCI: M+1: 455.2 (Exact Mass: 454.18).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07160888B2 |
| 出典データセット | uspto-grants-2007_01 |
| ORD ID | ord-7475b156f6684abc96ecb1fc988bb3e7 |
| 出典メモ | uspto-grants-2007_01 |