Veratraldehyde → HCID 69424807, compound

Participants

Reaction Steps

3-Aminopyrrolidine is reacted with 3-(3,4-dimethoxybenzaldehyde, which is commercially available from Aldrich (Milwaukee, Wis.) in an inert solvent, for example methanol, in the presence of a base, for example sodium carbonate, and stirred for about 4–24 hours, preferably about 12 hours, at about room temperature. When the reaction is substantially complete, 4-(2-aza-2-pyrrolidin-3-ylvinyl)-1,2-dimethoxybenzene is isolated and purified by conventional means, and used without further purification.

Provenance & Evidence