Tetrahydrofuran → 2-Chloro-5-[4-(3-methyl-piperidin-1-yl)-benzoyl]-benzenesulfonamide

HRID 137369Notes

Reaction equation

HRID 137369 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([CH3:14])[CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[C:32]([Li:33])([CH3:34])([CH3:35])[CH3:36].[Cl:15][c:16]1[c:17]([S:28]([NH2:29])(=[O:30])=[O:31])[cH:18][c:19]([C:20](=[O:21])[N:22]([O:23][CH3:24])[CH3:25])[cH:26][cH:27]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[c:2]1([C:20]([c:19]2[cH:18][c:17]([S:28]([NH2:29])(=[O:30])=[O:31])[c:16]([Cl:15])[cH:27][cH:26]2)=[O:21])[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([CH3:14])[CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 581073994-chloro-N-methoxy-N-methyl-3-sulfamoyl-benzamideHCID 668503451-(4-Bromo-phenyl)-3-methyl-piperidineHCID 178418306HCID 178418306, compound

Product 1

HCID 581074352-Chloro-5-[4-(3-methyl-piperidin-1-yl)-benzoyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-1c50810090c445829350e568b675bb56
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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