HuagongsheHuagongshe Chemistry Print Report · For research reference only
(7-Nitro-2,3-dihydro-1,4-benzodioxin-2-yl)methanol → (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (7-Nitro-2,3-dihydro-1,4-benzodioxin-2-yl)methanol | HCID 12736685 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol | HCID 22036433 | 86.9% |
Reaction Steps
4.2 g of the nitro compound from example k in 120 ml MeOH were hydrogenated at atmospheric pressure with 10% Pd—C at room temperature for 3 hrs. The mixture was filtered and the filtrate evaporated to yield 3.13 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07163941B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-628979ad81dc4a0cab63ae782ca236fd |
| Source note | uspto-grants-2007_01 |