Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethylene Oxide | HCID 6354 | — |
| Reactant | HCID 85154260 | HCID 85154260 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 73087119 | HCID 73087119 | 42% |
Reaction Steps
To a solution of the title compound of Example 39 (17.9 mg, 0.039 mmol) in MeOH (2 mL) at 0° C. was added ethylene oxide (0.4 mL). The reaction mixture was stirred at 4° C. overnight. The reaction mixture was concentrated and purified by chromatography to give the title compound as a white solid (8.2 mg, 42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07164011B2 |
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| Source dataset | uspto-grants-2007_01 |
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| ORD ID | ord-405446beb0664e1386609594c4bd5728 |
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| Source note | uspto-grants-2007_01 |
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