Diethyl Ether → 2-(3-Azetidinyl)-1H-imidazole

HRID 137450Notes

Reaction equation

HRID 137450 reaction equation
[B:22]([F:23])([F:24])[F:25].[CH2:17]([O:18][CH2:19][CH3:20])[CH3:21].[Cl:26][CH2:27][Cl:28].[nH:1]1[c:2]([CH:6]2[CH2:7][N:8]([C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[CH2:9]2)[n:3][cH:4][cH:5]1>>[nH:1]1[c:2]([CH:6]2[CH2:7][NH:8][CH2:9]2)[n:3][cH:4][cH:5]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6356Boron trifluorideHCID 58494519tert-Butyl 3-(1H-imidazol-2-yl)azetidine-1-carboxylate

Product 1

HCID 552991962-(3-Azetidinyl)-1H-imidazole

Sources & evidence

ORD record
ord-6eceed4fe6604957a6a9cb30e6147540
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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