Sodium borohydride → HCID 16638811, compound

HRID 1374540Notes

Reaction equation

HRID 1374540 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([O:10][CH:11]([CH3:13])[CH3:12])=[CH:4][C:3]=1[CH2:14][CH:15]=[O:16].[BH4-].[Na+]>C(O)C>[Br:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([O:10][CH:11]([CH3:13])[CH3:12])=[CH:4][C:3]=1[CH2:14][CH2:15][OH:16]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 57488769HCID 57488769, compound

Product 1

HCID 16638811HCID 16638811, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Bromo-5-(1-methylethoxy)-4-methoxybenzene acetaldehyde (2.60 g, 9.05 mmol) is added at 15° C. within 30 minutes to a suspension of sodium borohydride (0.341 g, 9.05 mmol) in absolute ethanol (40 ml), and it is stirred for two hours at this temperature.

Sources & evidence

ORD record
ord-e0d883e92b104a18b82704715825d718
Source dataset
uspto-grants-2007_01
Patent number
US07166588B2

Reaction notes

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