HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl malonate → HCID 16637924, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl malonate | HCID 7943 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, 1-(chloromethyl)-4-(1-methylethoxy)- | HCID 12249109 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 16637924 | HCID 16637924 | — |
Reaction Steps
1-(Chloromethyl)-4-(1-methylethoxy)benzene (20.5 g, 111 mmol), malonic acid dimethyl ester (102.5 g, 776 mmol) and potassium carbonate (46.5 g, 332 mmol, anhydrous, freshly ground) are stirred in absolute DMF (250 ml) for 24 hours at 70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07166588B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-348b4781162e47d9b7cc0228d2c279e0 |
| Source note | uspto-grants-2007_01 |