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HRID1374603

反应详情

EQUATION

反应方程式

HRID 1374603 的结构方程式

REACTANTS

反应物

3
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)[C@@H](N)Cc1ccccc1
HCID76506

Ethyl L-phenylalanate

C11H15NO2

结构：Cc1ccc(S(=O)(=O)N(C)[C@@H](Cc2ccccc2)C(=O)O)cc1
HCID12069251

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(S(=O)(=O)N(C)[C@@H](Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)O)cc1
HCID12069253

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

N-(Toluene-4-sulfonyl)-N-methylphenylalanine was coupled to L-phenylalanine ethyl ester using the procedure described in Method 3 (400 mg, 62%). The title compound was prepared via hydrolysis of the ethyl ester using NaOH in ethanol. Proton and carbon NMR analyis indicated a mixture of diastereomers.

WORKUP

后处理

  1. additiona mixture of diastereomers