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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1374641Generated: October 27, 2026

tert-Butyl (2-(3-nitrophenoxy)ethyl)carbamate → tert-butyl N-[2-(3-aminophenoxy)ethyl]carbamate

https://huagongshe.com/reaction/1374641

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (2-(3-nitrophenoxy)ethyl)carbamateHCID 21077618—
CatalystPlatinumHCID 23939—
SolventMethanolHCID 887—
Producttert-butyl N-[2-(3-aminophenoxy)ethyl]carbamateHCID 11557882—

Reaction Steps

Prepared from 3-[2-(tert.butyloxycarbonylamino)ethoxy]-nitrobenzene by hydrogenation in methanol at ambient temperature in the presence of platinum/charcoal, Rf value: 0.42 (silica gel; petroleum ether/ethyl acetate=1:1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07166599B2
Source datasetuspto-grants-2007_01
ORD IDord-c97434c57e6d4d90ab2ea25a1a786a7f
Source noteuspto-grants-2007_01