HCID 21077591, compound → HCID 21077605, compound

HRID 1374645Notes

Reaction equation

[CH3:1][S:2][C:3]1[N:8]=[C:7]([NH:9][CH3:10])[C:6]([Cl:11])=[CH:5][N:4]=1.I([O-])(=O)(=O)=[O:13].[Na+].C(Cl)Cl.CO.C(O)(=O)C.[OH2:27]>>[CH3:1][S:2]([C:3]1[N:8]=[C:7]([NH:9][CH3:10])[C:6]([Cl:11])=[CH:5][N:4]=1)(=[O:13])=[O:27]

Participants

Reactant 4

HCID 21077591HCID 21077591, compound

HCID 21226129Dichloromethane methanol

HCID 21899381Acetic acid--water (1/1)

HCID 23667635Sodium periodate

Product 1

HCID 21077605HCID 21077605, compound

Procedure

Prepared from 2-methylsulphenyl-4-methylamino-5-chloro-pyrimidine by reacting with sodium periodate in glacial acetic acid/water, Rf value: 0.50 (silica gel; methylene chloride/methanol=9:1)

Sources & evidence

ORD record: ord-3bcdf901c46b474eabfbfdca33fd70f4
Source dataset: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07166599B2

Reaction notes

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