Water → HCID 21077546, compound

HRID 1374656Notes

Reaction equation

HRID 1374656 reaction equation
[CH:1]1([NH2:4])[CH2:3][CH2:2]1.[Cl:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13]2[N:18]=[C:17](SC#N)[C:16]([N+:22]([O-:24])=[O:23])=[CH:15][N:14]=2)=[CH:8][CH:7]=1.O>CN(C)C=O>[Cl:5][C:6]1[CH:7]=[CH:8][C:9]([NH:12][C:13]2[N:14]=[C:15]([NH:4][CH:1]3[CH2:3][CH2:2]3)[C:16]([N+:22]([O-:24])=[O:23])=[CH:17][N:18]=2)=[CH:10][CH:11]=1

Participants

5

Reactant 3

HCID 962WaterHCID 69828CyclopropylamineHCID 21077556HCID 21077556, compound

Product 1

HCID 21077546HCID 21077546, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

0.93 g of cyclopropylamine are added to 1 g of 2-(4-chlorophenylamino)-4-thiocyanato-5-nitro-pyrimidine in 10 ml dimethylformamide and stirred for 1½ hours at ambient temperature. 30 ml of water are added, the solid is suction filtered, washed with water and dried.

Workup

  1. filtrationfiltered
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-83e7543e973b408dae8c644f7ddc0dff
Source dataset
uspto-grants-2007_01
Patent number
US07166599B2

Reaction notes

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