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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1374816Generated: October 31, 2026

1-Benzyl-4-(4-nitrobenzyl)piperazine → 4-[(4-Benzylpiperazin-1-yl)methyl]aniline

https://huagongshe.com/reaction/1374816

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-4-(4-nitrobenzyl)piperazineHCID 763935—
CatalystPalladiumHCID 23938—
Product4-[(4-Benzylpiperazin-1-yl)methyl]anilineHCID 18005713—

Reaction Steps

Prepared analogously to Example Id by catalytic hydrogenation of 1.3 g (4.2 mmol) of 4-(4-benzylpiperazinomethyl)-nitrobenzene over palladium/charcoal.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07166615B2
Source datasetuspto-grants-2007_01
ORD IDord-0ddf7f1db5774eb294d3b5bfb4613652
Source noteuspto-grants-2007_01