Potassium Hydroxide → HCID 2757211, compound

Participants

Reaction Steps

A solution of 1a (1.37 g, 3.73 mmol) in ethanol (20 mL) was mixed with KOH (627 mg, 11.2 mmol) in water (20 mL). The resultant mixture was heated at 60° C. for 1 h, diluted with HCl (50 mL, 1N) and extracted with ethyl acetate (60 mL, 3×). The combined organic phases were dried over MgSO4, filtered, and concentrated to afford compound 1b as a yellow solid.

Provenance & Evidence