Hydrochloric Acid → 5-(4-Fluorophenyl)-2-(piperidin-4-yloxy)pyridine

HRID 137509Notes

Reaction equation

HRID 137509 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[n:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[cH:19][cH:20]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:29][OH:30].[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[ClH:28]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[n:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 3283Diethyl EtherHCID 698966684-[5-(4-Fluorophenyl)pyridin-2-yloxy]piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 226467305-(4-Fluorophenyl)-2-(piperidin-4-yloxy)pyridine

Sources & evidence

ORD record
ord-dac25c389f4d4a27b65b345ba2ff327e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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