Hydrochloric Acid → HCID 19789957, compound

Participants

Reaction Steps

4,4-Diacetyl-heptanedioic acid di-tert-butyl ester was hydrolyzed at 95° C. over 5 hours using a mixture of tert-butanol and water as solvent and 11 weight-% hydrochloric acid. The solvent was removed and the obtained crude product was recrystallized from a mixture of acetone and petroleum ether (1:1) to yield 4,4-diacetyl-heptanedioic acid as white crystals at a yield of 69%. (melting point: 176° C.; purity 94%; colorless).

Provenance & Evidence