Hydrochloric Acid → HCID 12842290, compound

HRID 1375117Notes

Reaction equation

HRID 1375117 reaction equation
[Na+].[C:2]1([S:8]([O-:10])=[O:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:11]1(=[O:17])[CH2:16][CH2:15][CH2:14][CH:13]=[CH:12]1.Cl>O>[C:2]1([S:8]([CH:13]2[CH2:14][CH2:15][CH2:16][C:11](=[O:17])[CH2:12]2)(=[O:10])=[O:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 135942-Cyclohexen-1-oneHCID 2723840Benzenesulfinic acid, sodium salt

Product 1

HCID 12842290HCID 12842290, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Benzenesulfinic acid sodium salt (10.25 g) was added to a solution containing 5 ml of cyclohexenone and 30 ml of water, followed by the dropwise addition of 60 ml of 1N hydrochloric acid. The reaction mixture was stirred at room temperature for 24 hours. The crystals so precipitated were filtered and then washed with water, isopropanol and cold ethyl ether. After recrystallization from isopropanol, 5.74 g of 3-(phenylsulfonyl)-cyclohexan-1-one (m.p.: 83–85° C.) were obtained in the form of white crystals. Yield: 97%

Workup

  1. customThe crystals so precipitated
  2. filtrationwere filtered
  3. washwashed with water, isopropanol and cold ethyl ether
  4. customAfter recrystallization from isopropanol

Sources & evidence

ORD record
ord-440cc43f6ef549fd8b0d4140f3de93fe
Source dataset
uspto-grants-2007_01
Patent number
US07166642B1

Reaction notes

Loading…