HCID 86589523, compound → HCID 69023190, compound

HRID 1375282Notes

Reaction equation

HRID 1375282 reaction equation
C(OC([NH:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][C:19](=[O:23])[CH2:20][CH2:21][CH3:22])=[CH:14][C:13]=1C(CC)C([O-])=O)=O)C1C=CC=CC=1>CO.[Pd]>[C:19]([O:23][C:13]1[CH:14]=[C:15]([O:18][C:19](=[O:23])[CH2:20][CH2:21][CH3:22])[CH:16]=[CH:17][C:12]=1[NH2:11])(=[O:18])[CH2:20][CH2:21][CH3:22]

Participants

4

Reactant 1

HCID 86589523HCID 86589523, compound

Product 1

HCID 69023190HCID 69023190, compoundYield 96%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 2-benzyloxycarbonylamino-5-butyryloxyphenylbutanoate (KCBG04) KCBG04 (0.05 g, 0.12 mmol) in MeOH (5 mL) was added Pd/C (10%, 4 mg) at room temperature. After stirring for 20 min under H2, the reaction mixture was filtered and evaporated in vacuo to give 2-amino-5-butyryloxyphenyl butanoate (KCBG06, 0.031 g, 96%) as a white solid.

Workup

  1. filtrationthe reaction mixture was filtered
  2. customevaporated in vacuo

Sources & evidence

ORD record
ord-fc64397badbf427b8d33c5cba1585dcb
Source dataset
uspto-grants-2007_01
Patent number
US07166744B2

Reaction notes

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