Terephthalaldehyde → HCID 23062134, compound

HRID 1375306Notes

Reaction equation

HRID 1375306 reaction equation
[CH:1](=[O:10])[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[OH-].[K+]>CO>[CH3:1][C:2]1([CH3:9])[CH2:3][O:7][CH:6]1[C:5]1[CH:8]=[CH:9][C:2]([CH:1]2[C:5]([CH3:8])([CH3:6])[CH2:4][O:10]2)=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 12173TerephthalaldehydeHCID 14797Potassium Hydroxide

Product 1

HCID 23062134HCID 23062134, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

Isobutyl aldehyde of 4.2 equivalent amount and a 1.0 equivalent amount of terephthalaldehyde were dissolved in methanol, and a methanol solution of a 2.1 equivalent amount of potassium hydroxide was dropwise added thereto at room temperature. The resulting solution was reacted at 60° C. for 6 hours, and concentrated under reduced pressure. The concentrate was dissolved in water ten times the concentrate while heating and allowed to cool to precipitate crystals. The precipitated crystals were filtered off, washed with water, and dried over a drying agent for 2 days under reduced pressure to obtain white crystals, 1,4-bis(3,3-dimethyloxetan-2-yl)-benzene. The yield was 80 to 85%.

Workup

  1. customat room temperature
  2. customThe resulting solution was reacted at 60° C. for 6 hours
  3. concentrationconcentrated under reduced pressure
  4. dissolutionThe concentrate was dissolved in water ten times the
  5. concentrationconcentrate
  6. temperaturewhile heating
  7. temperatureto cool
  8. customto precipitate crystals
  9. filtrationThe precipitated crystals were filtered off
  10. washwashed with water
  11. customdried over a drying agent for 2 days under reduced pressure

Sources & evidence

ORD record
ord-2c1c1b165c1e47d09c2b3ff53fcbddd8
Source dataset
uspto-grants-2007_01
Patent number
US07169446B2

Reaction notes

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