1-Tetralone → 3349-64-2

Participants

Reaction Steps

To a solution of α-tetralone (50 g, 45.5 mL, 342 mmol) in anhydrous methanol (500 mL) was added hydroxylamine hydrochloride (24.7 g, 377 mmol) and sodium carbonate monohydrate (45 g, 363 mmol). The resulting slurry was stirred at ambient temperature for 36 h and the solvent was removed. The residue was titurated with water and the resulting solid was recrystallized from ether/hexanes to supply the product (37.1 g) as greenish tan crystals.

Provenance & Evidence