HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylamino)-2-[(4-morpholinophenyl)amino]-5-nitropyrimidine → 5-Amino-4-(methylamino)-2-[[4-(morpholin-4-yl)phenyl]amino]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylamino)-2-[(4-morpholinophenyl)amino]-5-nitropyrimidine | HCID 21077572 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 5-Amino-4-(methylamino)-2-[[4-(morpholin-4-yl)phenyl]amino]pyrimidine | HCID 58786812 | — |
Reaction Steps
Hydrogenation of 4-(methylamino)-2-[(4-morpholinophenyl)amino]-5-nitropyrimidine (from Example 2(1) above) over palladium on charcoal (Pd/C) gave the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169778B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-45b8ce954717485cac39ca91bb707f8e |
| Source note | uspto-grants-2007_01 |