HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-carbamic acid, 1,1-dimethylethyl ester → 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-carbamic acid, 1,1-dimethylethyl ester | HCID 86605432 | — |
| Reactant | [3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-carbamic acid, 1,1-dimethylethyl ester | HCID 86606803 | — |
| Product | 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | HCID 59154231 | — |
Reaction Steps
Utilising the procedure described in Example 91d, but employing [3-(5-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-carbamic acid, 1,1-dimethylethyl ester (Example 93c) in lieu of [3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-carbamic acid, 1,1-dimethylethyl ester, afforded the title compound as a colourless crystalline solid, m.p. 131–133° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169791B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-39d28372e2424da98c617c711cf75c12 |
| Source note | uspto-grants-2007_01 |