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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1375958Generated: November 5, 2026

Potassium Hydroxide → HCID 22499392, compound

https://huagongshe.com/reaction/1375958

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 20773936HCID 20773936—
SolventIsopropanolHCID 3776—
ProductHCID 22499392HCID 22499392107.3%

Reaction Steps

A mixture of intermediate (30) (0.0006 mol) and potassium hydroxide (0.006 mol) in isopropanol (5 ml) was stirred at room temperature overnight. The solvent was evaporated. The residue was dissolved in isopropanol/HCl 6N and converted into the hydrochloric acid salt. The precipitate was filtered off and dried, yielding 0.31 g of 4-[4-[[2-(2-furanyl)benzoyl]amino]phenyl]-α-phenyl-1-piperazineacetic acid (intermediate 31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07169796B2
Source datasetuspto-grants-2007_01
ORD IDord-73f8095899af4be3a1958b62646227fd
Source noteuspto-grants-2007_01