Carbon Tetrachloride → HCID 23080592, compound

HRID 1375982Notes

Reaction equation

HRID 1375982 reaction equation
C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH:20]([C:23]1[CH:24]=[CH:25][C:26]2[C:30](=[CH:31][CH:32]=1)[CH:29]=[C:28]([CH2:33]O)[CH:27]=2)([CH3:22])[CH3:21].C(Cl)(Cl)(Cl)[Cl:36]>>[Cl:36][CH2:33][C:28]1[CH:27]=[C:26]2[C:30](=[CH:31][CH:32]=[C:23]([CH:20]([CH3:22])[CH3:21])[CH:24]=[CH:25]2)[CH:29]=1

Participants

4

Reactant 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 23080561HCID 23080561, compound

Product 1

HCID 23080592HCID 23080592, compound

Procedure

Triphenylphosphine (0.66 g) was added to a solution of (6-isopropylazulen-2-yl)methanol (0.5 g) in carbon tetrachloride (10.0 ml) and the mixture was refluxed with heating for 15 hours. The reaction mixture was concentrated. The residue was purified by silica gel column chromatography (n-hexane-diethyl ether) to obtain 2-(chloromethyl)-6-isopropylazulene (0.38 g).

Workup

  1. temperaturethe mixture was refluxed
  2. temperaturewith heating for 15 hours
  3. concentrationThe reaction mixture was concentrated
  4. customThe residue was purified by silica gel column chromatography (n-hexane-diethyl ether)

Sources & evidence

ORD record
ord-bbf691e578b947dd8c62105c487dd665
Source dataset
uspto-grants-2007_01
Patent number
US07169761B2

Reaction notes

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