HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → HCID 58786571, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 1,1-Dimethylethyl 4-[2-amino-1-(2-fluorophenyl)ethyl]-1-piperazinecarboxylate | HCID 58786464 | — |
| Product | HCID 58786571 | HCID 58786571 | 97% |
Reaction Steps
To 4-[2-Amino-1-(2-fluoro-phenyl)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester (207) (1.0 g, 3.09 mmol) was added ethyl chloroformate (15 mL) and the reaction mixture is allowed to reflux for 18 h. The reaction mixture is then concentrated to dryness yielding 1.05 g (97%)product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07169777B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-cba296aeb1b24871bffcadb4c4833e93 |
| Source note | uspto-grants-2007_01 |