Methanesulfonyl chloride → HCID 58786455, compound

Participants

Reaction Steps

To a solution of the product from Step II (450 mg, 1.2 mmol) in CH2Cl2 (5 mL) was added TEA (0.35 mL, 2.44 mmol) and methanesulfonyl chloride (0.14 mL, 1.83 mmol). After stirring was 30 min at 23° C. the reaction was diluted with CH2Cl2 and washed with brine, dried (Na2SO4), and evaporated to give the title product as an oil. MS m/z 446.3 (M++1).

Provenance & Evidence