1-(4-Fluorophenyl)piperazine → N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide

HRID 137620Notes

Reaction equation

HRID 137620 reaction equation
[Cl:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([C:22]([CH3:23])([CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]1.[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH2:15][c:16]3[cH:17][cH:18][c:19]([C:22]([CH3:23])([CH3:24])[NH:25][C:26]([CH3:27])=[O:28])[cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 752601-(4-Fluorophenyl)piperazineHCID 18423089N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide

Product 1

HCID 11545168N-(1-methyl-1-(4-((4-(4-fluorophenyl)-piperazin-1-yl)methyl)phenyl)ethyl)acetamide

Sources & evidence

ORD record
ord-45bae394266a4bac866701d565d4bf6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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