反应详情

A mixture of 1,4,5-triphenylimidazol-2-one (15.3g), dibromoheptane (50.6g) and potassium carbonate (13.8g) was heated at reflux temperature in dry butanone (750m1) for.20 hours. The mixture was cooled, filtered and the flitrate evaporated to an oil which was chromatographed on silica gel (hexane/ethyl acetate) to give 1,4,5-triphenyl-3-(7-bromoheptyl)imidazole-2-one (11.1 g, 46%) as an oil.

1. temperaturewas heated
2. custom20 hours
3. temperatureThe mixture was cooled
4. filtrationfiltered
5. customthe flitrate evaporated to an oil which
6. customwas chromatographed on silica gel (hexane/ethyl acetate)