Potassium Carbonate → HCID 22916455, compound

HRID 1376389Notes

Reaction equation

HRID 1376389 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][NH:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[C:1]1([C:7]2[N:8]=[CH:9][N:10]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 264813Ethyl 8-bromooctanoateHCID 178418822HCID 178418822, compound

Product 1

HCID 22916455HCID 22916455, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

4-Phenylimidazole was treated with ethyl 8-bromooctanoate and potassium carbonate in butanone to give after work-up the title compound, m.p. 56°-57° C., Found: C, 72.8; H, 8.4; N, 9.0%; C19H26N2O2Requires: C, 72.6; H, 8.3;N, 8.9%

Sources & evidence

ORD record
ord-3ec83f56306345d79d389c4a944ccb83
Source dataset
uspto-grants-1997_09
Patent number
US05663053

Reaction notes

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