Tetrahydrofuran → HCID 178460807, compound

HRID 1376443Notes

Reaction equation

HRID 1376443 reaction equation
[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([SH:11])[N:3]=1.O1C[CH2:15][CH2:14][CH2:13]1>>[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([S:11][CH2:13][CH2:14][CH3:15])[N:3]=1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 178509033HCID 178509033, compound

Product 1

HCID 178460807HCID 178460807, compound

Procedure

2-Amino-6-propylthio-9H-purine was prepared by nucleophilic displacement of the iodo group on 1-iodopropane (Aldrich Chemical Co.) by 2-amino-6-mercapto-9H-purine (Aldrich Chemical Co.) in tetrahydrofuran.

Sources & evidence

ORD record
ord-a09046fb54fa47ad89bf6db35c9e09a9
Source dataset
uspto-grants-1997_09
Patent number
US05663154

Reaction notes

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