HuagongsheHuagongshe Chemistry Print Report · For research reference only
6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline → HCID 23193291, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline | HCID 15623 | — |
| Reactant | 2-((4-Nitrophenoxy)methyl)oxirane | HCID 21327 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 23193291 | HCID 23193291 | 95.5% |
Reaction Steps
A mixture of 1,2-epoxy-3-(4-nitrophenoxy)propane (4 g) and 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (5.4 g) in isopropanol (100 ml) was heated under reflux for 3 h and evaporated. The residue was purified by column chromatography to give the title compound (7.6 g) as a yellow oil which solidified on standing.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05663179 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-900a9a201c904822a4554b83c7ff98e8 |
| Source note | uspto-grants-1997_09 |