Diethyl Ether → HCID 86751196, compound

HRID 1376546Notes

Reaction equation

HRID 1376546 reaction equation
[N:1]1([NH:6][C:7]2[CH:16]=[CH:15][C:10]3[O:11][CH2:12][CH2:13][O:14][C:9]=3[C:8]=2[CH3:17])[CH2:5][CH2:4][N:3]=[CH:2]1.[C:18]([OH:25])(=[O:24])/[CH:19]=[CH:20]/[C:21]([OH:23])=[O:22].CCOCC>CO>[C:18]([OH:25])(=[O:24])/[CH:19]=[CH:20]/[C:21]([OH:23])=[O:22].[N:1]1([NH:6][C:7]2[CH:16]=[CH:15][C:10]3[O:11][CH2:12][CH2:13][O:14][C:9]=3[C:8]=2[CH3:17])[CH2:5][CH2:4][N:3]=[CH:2]1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 444972Fumaric AcidHCID 67575787HCID 67575787, compound

Product 1

HCID 86751196HCID 86751196, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.73 g of 6-(2-imidazolinylamino)-5-methylbenzodioxan and 0.861 g of fumaric acid are dissolved in 20 mL of methanol. The solution is heated and treated with about 20 mL of ether. After cooling, the crystals which formed are collected and found to be 2.14 g of 6-(2-imidazolinylamino)-5-methylbenzodioxan fumarate salt, which melts at 199°-201° C.

Workup

  1. temperatureThe solution is heated
  2. temperatureAfter cooling
  3. customthe crystals which formed
  4. customare collected

Sources & evidence

ORD record
ord-e80aee952c514a029adba49deb4b4ddb
Source dataset
uspto-grants-1997_09
Patent number
US05663189

Reaction notes

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