HRID1376683

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID76177

Succinimido (((benzyloxy)carbonyl)amino)acetate

C14H14N2O6

结构：CC(C)[C@H](NC(=O)[C@@H](N)CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

HCID15674433

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)CNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C

HCID131720160

未命名化合物

收率 87%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

By coupling Z-Gly-OSu and H-Asp(OtBu)-Val-OtBu there is obtained Z-Gly-Asp(OtBu)-Val-OtBu, m.p.132° C. (ethyl acetate), yield: 87%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1e0117dac1f14de8b694c3adce618605
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05663297
来源说明: uspto-grants-1997_09

反应 SMILES

[NH:1]([C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14])[CH2:2][C:3]([O:5]N1C(=O)CCC1=O)=O.[NH2:23][C@H:24]([C:33]([NH:35][C@H:36]([C:40]([O:42][C:43]([CH3:46])([CH3:45])[CH3:44])=[O:41])[CH:37]([CH3:39])[CH3:38])=[O:34])[CH2:25][C:26](=[O:32])[O:27][C:28]([CH3:31])([CH3:30])[CH3:29]>C(OCC)(=O)C>[NH:1]([C:13]([O:15][CH2:16][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)=[O:14])[CH2:2][C:3]([NH:23][C@H:24]([C:33]([NH:35][C@H:36]([C:40]([O:42][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:41])[CH:37]([CH3:39])[CH3:38])=[O:34])[CH2:25][C:26](=[O:32])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:5]