反应详情

To 135 g of 1-(2-methyl-5-nitrophenyl)guanidine nitrate (Japanese Unexamined Patent Publication (Kokai) No. 6-87834), 21 g of sodium hydroxide in 1.0 L of a cold aqueous solution was directly added, followed by stirring at room temperature for 10 minutes. The crystals were filtered, sufficiently washed with water and then forced-air dried at 60° C. to obtain 102 g of the objective compound as pale yellow crystals.

1. filtrationThe crystals were filtered
2. washsufficiently washed with water
3. customforced-air dried at 60° C.