Sodium Hydroxide → HCID 178426708, compound

HRID 13767Notes

Reaction equation

HRID 13767 reaction equation
[N+]([O-])(O)=O.[CH3:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[CH:8][C:7]=1[NH:15][C:16]([NH2:18])=[NH:17].[OH-].[Na+]>>[CH3:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[CH:8][C:7]=1[NH:15][C:16]([NH2:18])=[NH:17]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 178426711HCID 178426711, compound

Product 1

HCID 178426708HCID 178426708, compoundYield 100.1%

Procedure

To 135 g of 1-(2-methyl-5-nitrophenyl)guanidine nitrate (Japanese Unexamined Patent Publication (Kokai) No. 6-87834), 21 g of sodium hydroxide in 1.0 L of a cold aqueous solution was directly added, followed by stirring at room temperature for 10 minutes. The crystals were filtered, sufficiently washed with water and then forced-air dried at 60° C. to obtain 102 g of the objective compound as pale yellow crystals.

Workup

  1. filtrationThe crystals were filtered
  2. washsufficiently washed with water
  3. customforced-air dried at 60° C.

Sources & evidence

ORD record
ord-fa0ea5bd65864cb187b6153359d0c746
Source dataset
uspto-grants-2010_06
Patent number
US07728131B2

Reaction notes

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