HCID 11718687, compound → HCID 22918412, compound

HRID 1376769Notes

Reaction equation

HRID 1376769 reaction equation
[N+:1]([C:4]1[CH:31]=[CH:30][C:7]([NH:8][C:9]2[CH:10]=[C:11]3[C:16](=[O:17])[NH:15][C:13](=[O:14])[C:12]3=[CH:18][C:19]=2[NH:20][C:21]2[CH:26]=[CH:25][C:24]([N+:27]([O-])=O)=[CH:23][CH:22]=2)=[CH:6][CH:5]=1)([O-])=O>C1COCC1.[Ni]>[NH2:27][C:24]1[CH:25]=[CH:26][C:21]([NH:20][C:19]2[CH:18]=[C:12]3[C:13](=[O:14])[NH:15][C:16](=[O:17])[C:11]3=[CH:10][C:9]=2[NH:8][C:7]2[CH:30]=[CH:31][C:4]([NH2:1])=[CH:5][CH:6]=2)=[CH:22][CH:23]=1

Participants

4

Reactant 1

HCID 11718687HCID 11718687, compound

Product 1

HCID 22918412HCID 22918412, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A solution of 38 mg (0.09 mmol) of 4,5-bis(4-nitroanilino)phthalimide in 15 ml of THF is hydrogenated with 10% Raney nickel as catalyst for three hours at normal pressure and room temperature. The catalyst is filtered off and the reaction mixture is concentrated by evaporation, yielding the title compound in the form of a slightly yellowish powder: m.p. 154°-157° C., FAB-MS: 360 (M+ +H).

Workup

  1. filtrationThe catalyst is filtered off
  2. concentrationthe reaction mixture is concentrated by evaporation

Sources & evidence

ORD record
ord-c46cac240c3643b7b6fde1c3481dcb70
Source dataset
uspto-grants-1997_09
Patent number
US05663336

Reaction notes

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