Potassium Cation → 4-(4-Bromo-2-fluorophenylamino)-7-(2,3-epoxypropoxy)-6-methoxyquinazoline
Reaction equation
[Br:49][CH2:50][CH:51]1[O:52][CH2:53]1.[C:54](=[O:55])([O-:56])[O-:57].[Cl:1][c:2]1[cH:3][c:4]([F:26])[c:5]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH:23]4[CH2:24][O:25]4)[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:6][cH:7]1.[K+:58].[K+:59].[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[OH:27][c:28]1[cH:29][c:30]2[c:31]([c:32]([NH:33][c:34]3[cH:35][cH:36][c:37]([Br:45])[cH:38][c:39]3[F:40])[n:41][cH:42][n:43]2)[cH:44][c:46]1[O:47][CH3:48]>>[c:2]1([Br:45])[cH:3][c:4]([F:26])[c:5]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:21][CH2:22][CH:23]4[CH2:24][O:25]4)[c:16]([O:19][CH3:20])[cH:17][c:18]23)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-42265d0ab189443c86354f44ff7833b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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