HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-Bromonicotinoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-Bromonicotinic acid | HCID 88707 | — |
| Product | 5-Bromonicotinoyl chloride | HCID 2781223 | — |
Reaction Steps
To 5.00 g of 5-bromonicotinic acid, 74 ml of thionyl chloride was added and the mixture was heated at reflux for 6 hours. After the solvent was distilled off under reduced pressure, the crystal was washed with diisopropyl ether and collected by filtration to obtain 4.09 g of the objective compound as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728131B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-13b18ee5ae764080a25434c0db579b45 |
| Source note | uspto-grants-2010_06 |