Pyridine →

HRID 1376834Notes

Reaction equation

HRID 1376834 reaction equation
[C:1]([Cl:6])(=[O:5])[C:2]([Cl:4])=[O:3].[C:7](O)([CH3:10])([CH3:9])[CH3:8].N1C=CC=CC=1>CCOCC>[C:7]([ClH:4][C:2](=[O:3])[C:1]([Cl:6])=[O:5])([CH3:10])([CH3:9])[CH3:8]

Participants

4

Reactant 3

HCID 1049PyridineHCID 6386tert-ButanolHCID 65578Oxalyl chloride

Product 0

No Product data yet.

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

84 ml of oxalyl chloride in 800 ml of ether was cooled to -60° C. and over half-an-hour, a solution of 94 ml of tert.-butanol, 80 ml of pyridine and 200 ml of ether was added. The temperature was allowed to rise to 0° C. with stirring for a further hour. After filtering and concentrating the filtrate dryness, the residue was distilled under reduced pressure to obtain 93 g of tert-butyloxalic acid chloride boiling at 13 mm Hg, 45°-46° C.

Workup

  1. customto rise to 0° C.
  2. filtrationAfter filtering
  3. concentrationconcentrating the filtrate dryness
  4. distillationthe residue was distilled under reduced pressure

Sources & evidence

ORD record
ord-60bb2eb5e23745bd94338597933fbb12
Source dataset
uspto-grants-1997_09
Patent number
US05663164

Reaction notes

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