2-Methoxypropene → 4-[(1-Methoxy-1-methyl-ethoxyimino)-methyl]-pyridine

HRID 1376853Notes

Reaction equation

HRID 1376853 reaction equation
[CH3:1][O:2][C:3]([CH3:5])=[CH2:4].[N:6]1[CH:11]=[CH:10][C:9]([CH:12]=[N:13][OH:14])=[CH:8][CH:7]=1>C(Cl)Cl>[CH3:1][O:2][C:3]([CH3:5])([O:14][N:13]=[CH:12][C:9]1[CH:10]=[CH:11][N:6]=[CH:7][CH:8]=1)[CH3:4]

Participants

4

Reactant 2

HCID 83002-MethoxypropeneHCID 127644-Pyridinecarbaldehyde oxime

Product 1

HCID 545353694-[(1-Methoxy-1-methyl-ethoxyimino)-methyl]-pyridine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
60 °C

Procedure

1.5 ml of 2-methoxy-propene were added all at once to a suspension of 610 mg of pyridine-4-aldoxime in 10 ml of methylene chloride and the mixture was stirred for 18 hours at 60° C. under reduced pressure. The mixture was cooled and evaporated to dryness under reduced pressure to obtain 950 mg of 4-[(1-methoxy-1-methyl-ethoxyimino)-methyl]-pyridine.

Workup

  1. temperatureThe mixture was cooled
  2. customevaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-4c5a2ac97a544e49949dc727a88070c0
Source dataset
uspto-grants-1997_09
Patent number
US05663164

Reaction notes

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