HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137687Generated: October 25, 2026
4-(2,2,2-Trifluoroethyl)aniline → (5SR,6RS)-8-Benzyl-6-hydroxy-2-[4-(2,2,2-trifluoro-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one
https://huagongshe.com/reaction/137687
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-(2,2,2-Trifluoroethyl)aniline | HCID 14836858 | — |
| Reactant | 1-Benzyl-3-hydroxy-4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester | HCID 58056619 | — |
| Product | (5SR,6RS)-8-Benzyl-6-hydroxy-2-[4-(2,2,2-trifluoro-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one | HCID 58056622 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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| ORD ID | ord-bf02a88ec60d4754b0247adee2177c56 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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