Hydrochloric Acid → HCID 22918809, compound

Participants

Reaction Steps

A solution containing 7.6 g (0.029 moles) of 4-(5-acetoxy-2-hydroxy-3,4,6-trimethylphenyl)-2-methyl-1-butene in 90 ml of 95% ethyl alcohol, is added with 90 ml of a solution containing 14.9 g (0.264 moles) of potassium hydroxide in 95% ethyl alcohol. The reaction mixture is kept for 22 hours at 90° C., then is diluted by adding ethyl ether and water, acidified to pH 5 with a 10% aqueous solution of hydrochloric acid and the product is extracted with ethyl ether. The crude product is obtained by evaporation of the solvent and used without further purification.

Provenance & Evidence