Hydrochloric Acid → HCID 178441670, compound

Participants

Reaction Steps

186 mg (0.289 mmole) of the compound obtained in step 2 of Example 1 was dissolved in 3 ml of tetrahydrofuran and to the resulting solution was added 2 ml of aqueous 4N HCl solution. The resultant was stirred for 15 hours at room temperature, neutralized with aqueous 4N NaOH solution, concentrated under reduced pressure and purified with silica gel column chromatography to obtain 108 mg of the title compound (yield 71%).

Provenance & Evidence