反应详情

A solution of Oxone (84 g, 0.137 mol) in H2O (400 mL) was rapidly stirred as 3-chloro-4-ethylthio-1,2,5-thiadiazole (12.2 g, 0.067 mol) in THF (200 mL) was added. After stirring overnight, the THF was evaporated and the residue extracted with ether (3×). The extracts were washed with H2O, aqueous NaHCO3, and brine then the solvent dried and evaporated to give a clear liquid (13.6 g). (Compound 4).

1. additionwas added
2. customthe THF was evaporated
3. extractionthe residue extracted with ether (3×)
4. washThe extracts were washed with H2O, aqueous NaHCO3, and brine
5. customthe solvent dried
6. customevaporated