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HRID1377681

反应详情

EQUATION

反应方程式

HRID 1377681 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCC(Nc2ccccc2OCC(=O)O)CC1
HCID22380704

未命名化合物

结构：ClCCCl.On1nnc2ccccc21
HCID86583742

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(N2C(=O)COc3ccccc32)CC1
HCID22380676

1,1-Dimethylethyl 4-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-1-piperidinecarboxylate

C18H24N2O4

PROCEDURE

实验过程

1-t-Butyloxycarbonyl-4-((2-carboxymethoxyphenyl)amino)piperidine (5.2 g, 15 mmol) from Step 3 was cyclized using the EDC/HOBT coupling procedure given in Step 5 of Example 1. 4-(1-tert-butyloxycarbonyl-4-piperidinyl)-(2H)-1,4-benzoxazin-3(4H)-one was obtained as a foam (86% yield).