HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminonicotinic acid → (2-Aminopyridin-3-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminonicotinic acid | HCID 72930 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (2-Aminopyridin-3-yl)methanol | HCID 11159325 | — |
Reaction Steps
The methyl ester of 2-amino nicotinic acid is reduced with lithium aluminium hydride in a solvent such as THF to give 2-amino-3-hydroxymethylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05665719 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-a60b71f25bd048a5b3e9fdab000ee1cd |
| Source note | uspto-grants-1997_09 |