Ammonia → HCID 22915472, compound

Participants

Reaction Steps

The desired compound was prepared according to the method of Example 2, steps 2 and 3, except substituting 4-[4-(4-methoxyphenyl)phenoxy]butanoic acid ethyl ester, prepared as in step 1, for 4-(3-phenylphenoxy)butanoic acid ethyl ester. 1H NMR (CD3OD) δ 2.08 (dt, 2H, J=6.8, 13.6 Hz), 2.30 (t, 2H, J=7.4 Hz), 3.80 (s, 3H), 4.01 (t, 2H, J=6.0 Hz), 6.94 (d, 4H, J=8.8 Hz),7.46 (d, 2H, J=8.5 Hz), 7.46 (d, 2H, J=8.8 Hz). MS (DCI/NH3) 302 (M+H)+, 319 (M+NH4)+. Anal. Calcd for C17H19NO4 ·0.40H2O·0.60NH4Cl: C, 59.94; H, 6.57; N, 6.58. Found: C, 60.28; H, 6.50; N, 6.60.

Provenance & Evidence