Hydrochloric Acid → 1-Benzyl-4-chroman-2-ylmethyl-piperazine

HRID 1378323노트

반응식

HRID 1378323 반응식
Cl.[O:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH:3]1[C:12]([N:14]1[CH2:19][CH2:18][N:17]([CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH2:16][CH2:15]1)=O>>[O:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][CH:3]1[CH2:12][N:14]1[CH2:15][CH2:16][N:17]([CH2:20][C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:18][CH2:19]1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 104971031-[(Chroman-2-yl)carbonyl]-4-benzylpiperazine

생성물 1

HCID 107582001-Benzyl-4-chroman-2-ylmethyl-piperazine

실험 절차

By carrying out the preparation in the same way as in Example 1, but starting with the hydrochloride of 1-[(chroman-2-yl)carbonyl]-4-benzylpiperazine obtained in Stage A, the title compound is obtained.

후처리

  1. customthe preparation in the same way as in Example 1

출처 및 근거

ORD 기록
ord-8c3f4ac7bcc847a8bd462ec63ee19eeb
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05668138

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