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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1378327Generated: November 1, 2026

1-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine → 1-(2-Phenoxypropyl)-4-benzylpiperazine

https://huagongshe.com/reaction/1378327

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazineHCID 21472261—
Reactant1-(2-Phenoxypropionyl)-4-benzylpiperazine hydrochlorideHCID 21472266—
Product1-(2-Phenoxypropyl)-4-benzylpiperazineHCID 9796730—

Reaction Steps

By carrying out the preparation as in Example 1, but replacing 1-[(5-fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine with the 1-(2-phenoxypropionyl)-4-benzylpiperazine hydrochloride obtained in Example 7, the title product is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05668138
Source datasetuspto-grants-1997_09
ORD IDord-c982341893cc4ae0bcee43d8ed95726f
Source noteuspto-grants-1997_09