1,2-Ethanediamine, N1,N1,N2-trimethyl- → HCID 22909007, compound

HRID 1378981Notes

Reaction equation

HRID 1378981 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:31]([OH:34])(=[O:33])=O)[C:6](=[CH:27][C:28]=1[O:29][CH3:30])/[CH:7]=[CH:8]/[C:9]1[N:17]([CH3:18])[C:16]2[C:15](=[O:19])[N:14]([CH2:20][CH2:21][CH3:22])[C:13](=[O:23])[N:12]([CH2:24][CH2:25][CH3:26])[C:11]=2[N:10]=1.[CH3:35][N:36]([CH3:41])[CH2:37][CH2:38][NH:39][CH3:40]>>[CH3:35][N:36]([CH3:41])[CH2:37][CH2:38][N:39]([CH3:40])[S:31]([C:5]1[C:6](=[CH:27][C:28]([O:29][CH3:30])=[C:3]([O:2][CH3:1])[CH:4]=1)/[CH:7]=[CH:8]/[C:9]1[N:17]([CH3:18])[C:16]2[C:15](=[O:19])[N:14]([CH2:20][CH2:21][CH3:22])[C:13](=[O:23])[N:12]([CH2:24][CH2:25][CH3:26])[C:11]=2[N:10]=1)(=[O:34])=[O:33]

Participants

3

Reactant 2

HCID 673381,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 22909004HCID 22909004, compound

Product 1

HCID 22909007HCID 22909007, compoundYield 49.5%

Procedure

Substantially the same procedure as in Example 2 was repeated using 500 mg (0.98 mmol) of Compound 1 obtained in Example 1 and 0.62 mi (4.9 mmol) of N,N,N'-trimethyl-ethylenediamine. The resulting crude crystals were recrystallized from cyclohexane/toluene to give 280 mg (yield 48%) of Compound 6 as yellow needles.

Workup

  1. customThe resulting crude crystals were recrystallized from cyclohexane/toluene

Sources & evidence

ORD record
ord-496287a27f8c4a66a2c0907a4e27b241
Source dataset
uspto-grants-1997_09
Patent number
US05670498

Reaction notes

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