HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[4-(t-Butoxycarbonyl)piperazin-1-ylmethyl]-3-trifluoromethylbenzoic acid → 4-[4-(t-butoxycarbonyl)piperazin-1-ylmethyl]-3-trifluoromethyl-N-{3-[4-(5-bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylphenyl}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[4-(t-Butoxycarbonyl)piperazin-1-ylmethyl]-3-trifluoromethylbenzoic acid | HCID 23145899 | — |
| Reactant | 3-[4-(5-Bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylaniline | HCID 23145966 | — |
| Product | 4-[4-(t-butoxycarbonyl)piperazin-1-ylmethyl]-3-trifluoromethyl-N-{3-[4-(5-bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylphenyl}benzamide | HCID 23145942 | — |
Reaction Steps
This compound was prepared in the same manner as in Example 34, except that 4-[4-(t-butoxycarbonyl)piperazin-1-ylmethyl]-3-trifluoromethylbenzoic acid (Reference Example 13) and 3-[4-(5-bromopyridin-3-yl)pyrimidin-2-ylamino]-4-methylaniline (Reference Example 19) were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728131B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d63c0a04b7714bd48997ed15ef4025f9 |
| Source note | uspto-grants-2010_06 |